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Ramosetron-d3 hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Ramosetron-d3 (hydrochloride) is the deuterium labeled Ramosetron hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：318.82Formula：C17H15D3ClN3OCAS 号：1330266-04-0非标记 CAS：132036-88-5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (523 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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(E/Z-Triprolidine-d8 hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：(E/Z)-Triprolidine-d8 (hydrochloride) is the deuterium labeled (E/Z)-Triprolidine hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(E/Z)-Triprolidine-d8 hydrochloride 相关抗体:ADGRE1 (F4/80) Antibody (YA002)ADGRE1 (F4/80) Antibody (YA920)分子量：322.90Formula：C19H15D8ClN2CAS 号：1795134-06-3非标记 CAS：550-70-9运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (525 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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(±-Carbinoxamine-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：(±)-Carbinoxamine-d6 is the deuterium labeled (±)-Carbinoxamine[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：296.82Formula：C16H13D6ClN2OCAS 号：1216872-59-1非标记 CAS：3505-38-2运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (521 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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(Rac-Tamsulosin-d3 hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：(Rac)-Tamsulosin-d3 (hydrochloride) is the deuterium labeled (Rac)-Tamsulosin hydrochloride[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.(Rac)-Tamsulosin-d3 hydrochloride 相关抗体:BNSP AntibodyFACL4 AntibodyBrdU Antibody (YA578)GAPDH AntibodyGlucose 6 Phosphate Dehydrogenase AntibodyMETTL3 AntibodyTSG101 AntibodyAlkaline Phosphatase AntibodyCalnexin Antibody (YA573)Lamin A/C AntibodyLamin B1 AntibodyLAMP1 AntibodyLAMP2 Antibody (YA713)LAMP2a AntibodyNQO1 Antibody (YA697)NQO1 Antibody (YA261)OPA1 AntibodyRBM3 AntibodySynaptophysin Antibody (YA043)Laminin beta 1 AntibodyHeme Oxygenase 1 AntibodyKi67 Antibody (YA717)Ki67 Antibody (YA322)Asparagine Synthetase AntibodyCalnexin AntibodyKi67 Antibody (YA001)Osteopontin AntibodySynaptophysin Antibody (YA664)TREM2 AntibodyGAPDH Antibody (YA848)分子量：447.99Formula：C20H26D3ClN2O5SCAS 号：1189923-88-3非标记 CAS：80223-99-0运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann
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Alverine-d5 citrate「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Alverine-d5 (citrate) is the deuterium labeled Alverine citrate[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Alverine-d5 citrate 相关抗体:MTNR1A Antibody分子量：478.59Formula：C26H30D5NO7CAS 号：1215327-00-6非标记 CAS：150-59-4性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month纯度 & 产品资料纯度： 98.52%参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Glimepiride-d5，格列美脲 d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Glimepiride-d5 is the deuterium labeled Glimepiride. Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Glimepiride-d5 相关抗体:RAGE AntibodyPMP70 Antibody (YA1628)Amyloid Precursor Protein Antibody (YA1130)Serum Amyloid A Antibody (YA1168)DISC1 Antibody (YA2430)Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568)APLP2 Antibody (YA2722)LRRC15 Antibody (YA3182)Mint3 Antibody (YA3242)分子量：495.65Formula：C24H29D5N4O5SCAS 号：1028809-90-6非标记 CAS：93479-97-1中文名称：格列美脲 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (524 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Geisen, K., Special pharmacology of the new sulfonylurea glimepiride. Arzneimittelforschung, 1988. 38(8): p. 1120-30. [Content Brief][3]. Liu, F., et al., Glimepiride attenuates Abeta production via suppressing BACE1 activit
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Propylthiouracil-d5，6-n-Propylthiouracil-d5; 6-Propyl-2-thiouracil-d5; PTU-d5「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Propylthiouracil-d5 is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：175.26Formula：C7H5D5N2OSCAS 号：1189423-94-6非标记 CAS：51-52-5中文名称：丙硫氧嘧啶 d5运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (526 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief][2]. Nakamura, H., et al., Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocrinol Metab, 2007. 92(6): p. 2157-62. [Content Brief][3]. Taurog, A. and M.L. Dorris, A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil. Endocrinology, 1989. 124(6): p. 3038-42. [Content Brief]
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Chlorpheniramine-d6 maleate「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Chlorpheniramine-d6 (maleate) is the deuterium labeled Chlorpheniramine maleate[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：396.90Formula：C20H17D6ClN2O4CAS 号：1219806-45-7非标记 CAS：113-92-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (517 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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(Rac-Remelteon-d3「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：(Rac)-Remelteon-d3 is the deuterium labeled (Rac)-Remelteon[1].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：262.36Formula：C16H18D3NO2CAS 号：1185146-24-0非标记 CAS：196597-17-8运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (519 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
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Promethazine-d6 hydrochloride，(±-Promethazine-d6 (hydrochloride「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Promethazine-d6 (hydrochloride) is the deuterium labeled Promethazine hydrochloride. Promethazine hydrochloride is an orally active histamine receptor antagonist[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Promethazine-d6 hydrochloride 相关抗体:ADGRE1 (F4/80) Antibody (YA002)ADGRE1 (F4/80) Antibody (YA920)分子量：326.92Formula：C17H15D6ClN2SCAS 号：1189947-02-1非标记 CAS：58-33-3性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.纯度 & 产品资料Data Sheet (531 KB)产品使用指南 (1538 KB)参考文献[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief][2]. Burt DR, et al. Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain. Science. 1977 Apr 15;196(4287):326-8. [Content Brief]
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IDH1 Inhibitor 7-d2「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：IDH1 Inhibitor 7-d2 is the deuterium labeled IDH1 Inhibitor 7 (HY-150238). IDH1 Inhibitor 7 is an IDH1 inhibitor with an IC50 of less than 100 nM[1][2].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.IDH1 Inhibitor 7-d2 相关抗体:IDH1 AntibodyAconitase 2 Antibody (YA2151)Aconitase 1 Antibody (YA2850)分子量：461.48Formula：C22H22D2F3N7OCAS 号：2135309-51-0非标记 CAS：2135309-56-5性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Selexipag-d7「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Selexipag-d7 is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor)[1][2].IC50 & Target：IP体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.Selexipag-d7 相关抗体:Prostaglandin D Synthase Antibody (YA1739)DP1 Antibody (YA2766)分子量：503.66Formula：C26H25D7N4O4SCAS 号：1265295-21-3非标记 CAS：475086-01-2性状：固体颜色：White to off-white运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Teneligliptin-d8，MP-513 d8「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Teneligliptin-d8 is a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting DPP-4 inhibitor[1].IC50 & Target：DPP-4Clinical TrialNCT NumberSponsorConditionStart DatePhaseNCT02449330National Cerebral and Cardiovascular CenterDiabetes Mellitus, Type 2June 2015Phase 4NCT02924064Mitsubishi Tanabe Pharma CorporationType 2 Diabetes MellitusSeptember 2016Phase 3NCT02567994Handok Inc.Type 2 Diabetes MellitusApril 2015Phase 3 NCT00628212Mitsubishi Tanabe Pharma CorporationType 2 DiabetesJanuary 2008Phase 2NCT03769870Handok Inc.Diabete MellitusJanuary 11, 2019Phase 1NCT05504239Handok Inc.Type 2 DiabetesOctober 2022Phase 3NCT03793023Handok Inc.Type 2 Diabetes MellitusJanuary 2016NCT04431141Handok Inc.Type 2 Diabetes MellitusSeptember 15, 2020Phase 1NCT02512523Handok Inc.Type 2 Diabetes MellitusAugust 2015Phase 4NCT02314637Mitsubishi Tanabe Pharma CorporationType 2 Diabetes MellitusAugust 2009Phase 3NCT02354222Mitsubishi Tanabe Pharma CorporationType 2 Diabetes MellitusJanuary 2015Phase 3NCT02354235Mitsubishi Tanabe Pharma CorporationType 2 Diabetes MellitusJanuary 2015Phase 3NCT01798238Handok Inc.Type 2 Diabetes MellitusNovember 2012Phase 3NCT00971243Mitsubishi Tanabe Pharma CorporationType 2 Diabetes MellitusAugust 2009Phase 2NCT04446026Yonsei UniversityType 2 Diabetes MellitusJuly 8, 2020Phase 4NCT03011177Handok Inc.Type2 Diabetes MellitusJanuary 2017Phase 4NCT01805830Handok Inc.Type 2 DiabetesMay 2012Phase 3NCT00974090Mitsubishi Tanabe Pharma CorporationType 2 Diabetes MellitusSeptember 2009Phase 3NCT02916706M
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Cariprazine-d6，RGH-188-d6「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Cariprazine-d6 is a deuterium labeled Cariprazine. Cariprazine Cariprazine is an antipsychotic agent that exhibits high affinity for the D3 (Ki of 0.085 nM) and D2 (Ki of 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki of 2.6 nM)[1].IC50 & Target[1]：Dopamine D2 Receptor0.49 nM (Ki)Dopamine D3 Receptor0.085 nM (Ki)5-HT1A Receptor2.6 nM (Ki)分子量：433.45Formula：C21H26D6Cl2N4OCAS 号：1308278-67-2非标记 CAS：839712-12-8性状：固体颜色：White to off-white中文名称：卡利拉嗪 d6运输条件：Room temperature in continental US; may vary elsewhere.储存方式：Powder：-20°C：3 years，4°C：2 yearsIn solvent：-80°C：6 months，-20°C：1 month
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Pyronaridine-d4 tetraphosphate，磷酸咯萘啶-d4「同位素标记抑制剂」
作者：德尔塔生物 日期：2025-09-17
生物活性：Pyronaridine-d4 (tetraphosphate) is the deuterium labeled Pyronaridine tetraphosphate[1]. Pyronaridine tetraphosphate is an orally active Mannich base anti-malarial agent. Pyronaridine tetraphosphate is active against P. falciparum and Echinococcus granulosus infection[2][3].体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].德尔塔生物 has not independently confirmed the accuracy of these methods. They are for reference only.分子量：914.06Formula：C29H40D4ClN5O18P4CAS 号：1186026-25-4非标记 CAS：76748-86-2性状：固体颜色：Light yellow to yellow中文名称：磷酸咯萘啶-d4运输条件：Room temperature in continental US; may vary elsewhere.储存方式：4°C, sealed storage, away from moisture*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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